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Interaction Checker

Check interactions between medicines, food, drink, conditions and pregnancy in seconds. Based on validated pharmacological references and official sources.

Drugs to check
Add a second drug to compare specific pairs, or explore all interactions of the first one.

Clinical and educational support tool. The information does not replace a medical prescription or the opinion of a qualified healthcare professional. Always confirm with specialised literature and professional judgement before any therapeutic decision.

Add a drug to see its documented interactions across all types.

Sources and references

Drug–drug interactions are anchored to FDA-approved labels (DailyMed/NIH) and publicly accessible NIH clinical sources (MedlinePlus, PubMed). The food, disease and pregnancy dimensions follow EMC-UK (MHRA) as the canonical source, corroborated by Health Canada. Official European SmPCs can be consulted on the EMA and, in Portugal, on the INFARMED portal.

  • DailyMed — FDA-approved labels (NIH/NLM)
  • MedlinePlus — drug monographs (NIH/NLM)
  • PubMed — indexed biomedical literature (NIH/NLM)
  • EMA — European medicines information in Portuguese
  • INFARMED — SmPC (official Portuguese portal, via Infomed)
  • EMC-UK — Summaries of Product Characteristics (MHRA, UK)
  • Health Canada — Product Monographs (DPD)

Frequently asked questions about the checker

Answers to common questions about how interaction checking works.

Which types of interactions are checked?
The checker covers four types: drug–drug, drug–food or drink, drug–disease and drug–pregnancy/breastfeeding. Each type has its own tab for quick access.
What is an interaction?
An interaction happens when a medicine, food, drink, disease or condition changes how another medicine acts in the body — increasing or decreasing its effect, or creating a new risk. Not every combination is dangerous, but some require monitoring or dose adjustment.
How are the severities determined?
We classify interactions as Critical, Moderate and Minor based on reference literature. Severity reflects the likelihood and potential seriousness of the event, not an individual certainty.
What does “Not assessed” mean?
It means there is no documented information for that selection in our database yet. The absence of a record does not mean no interaction exists — always confirm with a healthcare professional and reference literature.
Does the tool replace medical evaluation?
No. This is an educational support tool. The therapeutic decision always belongs to a qualified healthcare professional who considers the patient as a whole.
Which sources are used?
Drug–drug interactions are anchored to FDA-approved labels (DailyMed/NIH) and NIH clinical sources (PubMed). The food, disease and pregnancy dimensions follow EMC-UK (MHRA) as the canonical source, corroborated by Health Canada. Official European SmPCs can be consulted on the EMA and, in Portugal, on the INFARMED portal (Infomed).
Can I check more than two drugs at once?
Yes. Add as many drugs as you want; the pairs among all selected drugs are calculated.