Clonazepam is a benzodiazepine used for epilepsy (absence, myoclonic) and panic disorder.
Also known as: clonazepam, rivotril
Long half-life benzodiazepine. Broad-spectrum anticonvulsant.
Binding to the benzodiazepine site of GABA-A. More pronounced anticonvulsant effect than other benzodiazepines.
Complete oral absorption. Bioavailability: 90-100%.
Metabolised by CYP3A4. Inactive metabolites.
18-50 h.
No documented drug–drug interactions for this medicine.
Alcohol adds CNS depression and may impair seizure control; the combination is discouraged.
Avoid alcohol during treatment.
EMC-UK — Clonazepam SmPC 4.5 (alcohol); Prontuário 10.1 (l. 30138).
No documented disease interactions.
No documented pregnancy or breastfeeding information.
Clinical and educational support tool. The information does not replace a medical prescription or the opinion of a qualified healthcare professional.
Medicines from the same therapeutic group (ATC classification) or the same pharmacological class.
